Exosomes derived from ovarian cancer have enhanced tube formation ability both in vitro and in vivo. A. 10 µg/ml exosomes purified from CAOV3 induce tube formation of endothelial cells to a greater extent in contrast to those at the concentration of 50 µg/ml derived from SKOV3. B. Property of tube analysis indicated the means ± standard deviation (SD), n = 3; *P < 0.05, **P < 0.01. C. Just as in vitro study, 10 µg/ml exosomes derived from CAOV3 induce CAMs vessel formation to a greater extent in contrast to those at the concentration of 50 µg/ml purified from SKOV3. D. Property of vessels analysis around membranes within 1 mm diameter signified the means ± standard deviation (SD), n = 3; *P < 0.05, ***P < 0.001. E. Property of vessels analysis around membranes within 5 mm diameter indicated the means ± standard deviation (SD), n = 3; *P < 0.05, **P < 0.01.