Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
KLF4 is a target of miR-10b. A. KLF4 3’-UTR and corresponding fragments were inserted into the region immediately downstream of the luciferase gene in pRL-TK Vector and validated by DNA sequencing. The sequences of the predicted miR-10b binding sites within the KLF4 3’-UTR, including wild-type UTR or UTR segments containing mutant binding site are shown. B. Ectopic miR-10b expression inhibits wild-type but not mutant KLF4 3’-UTR reporter activity, *P < 0.001.
