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APOBEC3B knockdown could enhance the cytotoxicity of PDCD2 in MKN28 cells. A: The percentages of growth inhibition were determined by MTT assay; B: Flow cytometric cell cycle assay by using PI staining; C: Deep sequencing detected APOBEC3B-induced editing in PDCD2. MKN28: untreated MKN28 cells, MKN28-P: PDCD2 positive MKN28 cells, MKN28-P+S: PDCD2 positive MKN28 transfected with APOBEC3B shRNA plasmid.
