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Effect of bevacizumab on the induction of apoptosis in A549 cells as determined by fiow cytometry. A. A549 cells were treated with bevacizumab at indicated concentrations for 12 hr, then stained with annexin V and propidium iodide (PI), followed by detection using fiow cytometry. B. The percentage of cells with early apoptosis and late apoptosis are shown. Statistically significant, #P<0.05, ##P<0.05, t-test vs. vehicle control.
