Table 1.
Comparison of clinicopathological characteristics of Xp11.2 RCC and CCRCC
| Xp11.2 RCC (n=22) | CCRCC (n=32) | P | |
|---|---|---|---|
| Gender (male/female) | 9/13 | 22/10 | 0.042 |
| Age: mean ± SE (range, years) | 25.8±2.5 (3~51) | 60.2±2.2 (40~81) | <0.001 |
| Gross hematuria incidence | 9/22 (40.9%) | 0/32 (0%) | <0.001 |
| Tumor diameter: mean ± SE (range, cm) | 5.28±0.45 (3.0~10.0) | 3.80±0.23 (2.0~6.2) | 0.002 |
| Pseudocapsule incidence (percentage) | 14/22 (63.6%) | 32/32 (100.0%) | <0.001 |
| Pseudocapsule integrity rate (percentage) | 10/14 (71.4%) | 23/32 (71.9%) | 1.000 |
| Numbers of small/large tumors (threshold: 7 cm) | 17/5 | 31/1 | 0.036 |
| Age of small tumors: Mean ± SE (range, years) | 25.5±2.9 (3~51) | 59.7±2.2 (40~81) | <0.001 |
| Diameter of smaller tumors (Mean ± SE, cm) | 4.27±0.24 | 3.72±0.22 | 0.118 |
| Diameter of larger tumors (Mean ± SE, cm) | 8.72±0.33 | -- | -- |
| Pseudocapsule incidence of small tumors (%) | 13/17 (76.5%) | 32/32 (100%) | 0.011 |
| Pseudocapsule incidence of large tumors (%) | 1/5 (20.0%) | -- | -- |
| Pseudocapsule integrity rate of small tumors (%) | 9/13 (69.2%) | 23/32 (71.9%) | 0.711 |
| Pseudocapsule integrity rate of large tumors (%) | 1/1 (100%) | -- | -- |
| Pseudocapsule penetration information | 3 cases ≥4 cm 1 case =3.9 cm | 8 cases ≥4 cm 1 case =3.5 cm | 1.000 |
Xp11.2 RCC, renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion; CCRCC, clear cell renal cell carcinoma; SE, standard error.