Table 1.

Clinical characteristics according to TMPRSS3 expression in BC

Clinicopathological variables	Number of patients	High TMPRSS3 expression n=105	Low TMPRSS3 expression n=44	P value
Age
<50 years	64	46 (43.8%)	18 (40.9%)	0.744
≥50 years	85	59 (56.2%)	26 (59.1%)
Menopausal status
Premenopausal	80	55 (52.4%)	25 (56.8%)	0.620
Postmenopausal	69	50 (47.6%)	19 (43.2%)
TNM stage
I-II	108	71 (67.6%)	37 (84.1%)	0.040*
III-IV	41	34 (32.4%)	7 (15.9%)
ER status
Negative	83	57 (54.3%)	26 (59.1%)	0.590
Positive	66	48 (45.7%)	18 (40.9%)
PR status
Negative	72	50 (47.6%)	22 (50%)	0.791
Positive	77	55 (52.4%)	22 (50%)
Her-2 status
Negative	40	25 (23.8%)	15 (34.1%)	0.196
Positive	109	80 (76.2%)	29 (65.9%)
LN metastasis
Negative	75	46 (43.8%)	29 (65.9%)	0.014*
Positive	74	59 (56.2%)	15 (34.1%)
ki-67 status
Negative	36	31 (29.7%)	23 (53.1%)	0.008**
Positive	60	74 (70.3%)	21 (46.9%)

^* P<0.05;

^** P<0.01.