Table 2.
Survival analysis in the whole population
| OS(overall survival) | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| Variables | Univariate HR (95% CI) | P* | Multivariate HR (95% CI) | P* | ||
| Age (years) | > 61 | 1.0 | 0.831 | 1.0 | 0.081 | |
| ≤ 61 | 0.965 (0.733-1.923) | 0.548 (0.304-1.098) | ||||
| Gender | Male | 1.0 | 0.443 | 1.0 | 0.351 | |
| Female | 0.677 (0.423-1.883) | 1.357 (0.714-2.577) | ||||
| Smoking history | Never smoker | 1.0 | 0.993 | 0.484 (0.245-1.050) | 0.053 | |
| Smoker | 0.666 (0.563-1.965) | 1.0 | ||||
| Pathology | Squamous | 1.0 | 0.412 | 1.0 | 0.082 | |
| Adenocarcinoma | 0.552 (0.364-1.324) | 2.643 (1.455-2.800) | ||||
| Stage | I | 1.0 | 0.000 | 1.0 | 0.000 | |
| II | ||||||
| III | 1.965 (1.634-2.438) | 1.838 (1.346-2.510) | ||||
| Adjuvant | not received | 1.0 | 0.265 | 1.0 | 0.095 | |
| received | 1.242 (0.973-1.839) | 1.503 (0.915-1.936) | ||||
| CD133 | negative | 1.0 | 0.035 | 1.0 | 0.010 | |
| Positive | 1.965 (1.723-2.475) | 0.370 (0.174-0.788) | ||||
| CD133/MAGE-A4 | negative | 1.0 | 0.000 | 1.0 | 0.000 | |
| Positive | 1.834 (1.572-2.436) | 1.944 (1.396-2.707) | ||||
| CD133/NY-ESO-1 | negative | 1.0 | 0.000 | 1.0 | 0.002 | |
| Positive | 0.973 (0.678-1.823) | 1.660 (0.949-1.965) | ||||
| CD133/MAGE-A10 | negative | 1.0 | 0.001 | 1.0 | 0.094 | |
| Positive | 1.892 (0.932-2.421) | 1.365 (0.932-2.421) | ||||
| Gene analysis | Activated | 1.0 | 1.0 | |||
| Wild type | 0.624 (0.238-1.214) | 0.421 | 0.573 (0.325-1.011) | 0.054 | ||
| Unknown | ||||||
*
Represent P < 0.05.