Table 3.
Comparison of rs1799724 and rs266085 genotype and allele frequencies in cervical cancer in situ and invasive cervical cancer
| SNP | In situ (%) | Invasive (%) | Model | ||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| N=121 | N=227 | OR (95 CI) | P-value | Model | OR (95% CI) | P-value | |
| rs1799724 | |||||||
| Genotype | |||||||
| CC/CC | 75 (62.0) | 140 (61.7) | 1.00 (reference) | Dom | 0.99 (0.63-1.55) | 0.96 | |
| TC/TC | 32 (26.4) | 55 (24.2) | 1.09 (10.65-1.82) | 0.76 | Rec | 0.80 (0.41-1.56) | 0.51 |
| TT/TT | 14 (11.6) | 32 (14.1) | 0.82 (0.41-1.63) | 0.56 | Add | 0.95 (0.69-1.29) | 0.73 |
| Alleles | |||||||
| CC Alleles | 75.2 | 73.8 | 1.00 (reference) | 0.68 | |||
| TT Alleles | 24.8 | 26.2 | 0.93 (0.65-1.33) | ||||
| Rs266085 | |||||||
| Genotype | |||||||
| CC/CC | 25 (20.6) | 48 (21.1) | 1.00 (reference) | Dom | 1.03 (0.60-1.77) | 0.92 | |
| TC/TC | 55 (45.5) | 86 (37.9) | 1.23 (0.68-2.22) | 0.50 | Rec | 0.74 (0.47-1.17) | 0.20 |
| TT/TT | 41 (33.9) | 93 (41.0) | 0.85 (0.46-1.55) | 0.59 | Add | 0.89 (0.66-1.19) | 0.43 |
| Alleles | |||||||
| CC Alleles | 43.4 | 40.8 | 1.00 (reference) | 0.40 | |||
| TT Alleles | 56.6 | 59.2 | 0.87 (0.64-1.20) | ||||