Table 2.
Relationship between three polymorphisms of RET with TC risk
| Genotype/allelotype | Cases (n=135) | Controls (n=135) | χ2 | P value | OR (95% CI) |
|---|---|---|---|---|---|
| rs1799939 | |||||
| GG | 92 | 104 | - | - | 1 |
| GA | 33 | 28 | 0.96 | 0.38 | 1.33 (0.75-2.37) |
| AA | 10 | 3 | 4.39 | 0.046 | 3.77 (1.01-14.11) |
| G | 217 (80.4%) | 236 (87.4%) | - | - | 1 |
| A | 53 (19.6%) | 34 (12.6%) | 4.95 | 0.035 | 1.70 (1.06-2.71) |
| rs1800858 | |||||
| AA | 24 | 39 | - | - | 1 |
| AG | 70 | 65 | 3.26 | 0.093 | 1.75 (0.95-3.22) |
| GG | 41 | 31 | 4.78 | 0.038 | 2.15 (1.08-4.29) |
| A | 118 (43.7%) | 143 (53.0%) | - | - | 1 |
| G | 152 (56.3%) | 127 (47.0%) | 4.64 | 0.039 | 1.45 (1.03-2.04) |
| rs74799832 | |||||
| TT | 63 | 79 | - | - | 1 |
| TC | 52 | 45 | 1.97 | 0.19 | 1.45 (0.86-2.43) |
| CC | 20 | 11 | 4.14 | 0.049 | 2.28 (1.02-5.11) |
| T | 178 (65.9%) | 203 (75.2%) | - | - | 1 |
| C | 92 (34.1%) | 67 (24.8%) | 5.57 | 0.023 | 1.57 (1.08-2.28) |