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Histograms (bin size = 10 μm) of aggregate size as measured by effective diameter at A) day 0 pre-encapsulation, B) day 28 for the unencapsulated aggregates, and C) day 28 for the encapsulated aggregates. Inset images are from brightfield microscopy. Scale bar = 100 μm. D) The average aggregate effective diameter at days 0, 14, and 28. Data are presented as the mean with standard deviation as error bars for n=3–4 independent experiments. P-values are compared to day 0.
