Table 2.
Comparisons of demographics and clinical characteristics based on referral for genetic counseling (GC) and whether genetic services were accessed
| Referred for GC N=152 | Not referred N=288 | P-value | Accessed services N=180 | Not accessed N=260 | P-value | |
|---|---|---|---|---|---|---|
| Age at first breast cancer (n (%)) | ||||||
| ≤40 years | 76 (50) | 90 (31) | <0.001* | 95 (53) | 71 (27) | <0.001* |
| 41-45 years | 37 (24) | 83 (29) | 44 (24) | 76 (29) | ||
| 46-50 years | 39 (26) | 115 (40) | 41 (23) | 113 (43) | ||
| Insurance at diagnosis (n (%)) | ||||||
| Private | 94 (62) | 144 (50) | 0.009* | 128 (71) | 110 (42) | <0.001* |
| Governmenta | 44 (29) | 120 (42) | 39 (22) | 125 (48) | ||
| Unknownb | 14 (9) | 24 (8) | 13 (7) | 25 (10) | ||
| Annual household income (n (%)) | ||||||
| <$35,000 | 61 (40) | 155 (54) | 0.003* | 62 (34) | 154 (59) | <0.001* |
| ≥$35000 | 82 (54) | 112 (39) | 109 (61) | 65 (25) | ||
| Unknownb | 9 (6) | 21 (7) | 9 (5) | 21 (8) | ||
| Education (n (%)) | ||||||
| College graduate | 80 (53) | 95 (33) | <0.001* | 97 (54) | 78 (30) | <0.001* |
| Some college or vocational training | 47 (31) | 108 (38) | 60 (33) | 95 (36) | ||
| <High school/GED | 25 (16) | 83 (29) | 23 (13) | 85 (33) | ||
| Unknownb | 0 | 2 (1) | 0 | 2 (1) | ||
| Receptor status (n (%))c | ||||||
| Triple negative | 43 (28) | 58 (20) | 0.107 | 53 (29) | 48 (18) | 0.009* |
| Non-triple negative | 101 (66) | 199 (69) | 113 (63) | 187 (72) | ||
| Unknownb | 8 (5) | 31 (11) | 14 (8) | 25 (10) | ||
| Family history of ovarian cancer (n (%))d | ||||||
| Yes | 26 (17) | 33 (11) | 0.098 | 27 (15) | 32 (12) | 0.415 |
| No | 126 (83) | 255 (89) | 153 (85) | 228 (88) | ||
| Family history of breast cancer (n (%))d | ||||||
| Yes | 92 (61) | 156 (54) | 0.201 | 111 (62) | 137 (53) | 0.062 |
| No | 60 (39) | 132 (46) | 69 (38) | 123 (47) | ||
| Risk for carrying a BRCA mutation (n (%))e | ||||||
| >10% risk | 53 (35) | 95 (33) | 0.642 | 62 (34) | 86 (33) | 0.747 |
| ≤ 10% risk | 95 (62) | 188 (65) | 114 (63) | 169 (65) | ||
| missing | 4 (3) | 5 (2) | 4 (2) | 5 (2) | ||
| Married or cohabiting (n (%))e | ||||||
| Yes | 62 (41) | 115 (40) | 0.906 | 76 (42) | 101 (39) | 0.420 |
| No | 90 (59) | 171 (59) | 102 (57) | 159 (61) | ||
| Unknown | 0 | 2 (1) | 2 (1) | 0 | ||
| Children (n (%)) | ||||||
| Yes | 134 (88) | 252 (88) | 0.841 | 156 (87) | 230 (90) | 0.573 |
| No | 18 (12) | 36 (12) | 24 (13) | 30 (11) |
Statistically significant at p<0.05
Government insurance includes Medicare, Medicaid, Indian health services, and Military.
Unknown were not included in analyses.
Numbers for whom receptor status is known differ from Table 1 because study participants who were positive for any one of the three receptors (ER, PR, or HER2) were coded as non-triple negative and receptor status was determined through medical records or self-report for others.
One or more first, second, or third degree relatives affected.
Calculated using pedigree data and Myriad risk assessment prevalence table.
f Number of married participants differs from Table 1 given that marital status from baseline surveys are reported here.