The effects of p27SJ and p38SJ on the promoter activity of the HIV-1 LTR were examined using the HIV-1 LTR-luciferase reporter construct in the p27SJ-inducible cell line (Fig. 6). In this experiment, the effect of Tat, p65 and both together were measured with and without doxycycline to induce p27SJ. Each column was normalized to the control in column 1 (100%), i.e., in the absence of Tat, p65, p27SJ (-Dox) and p38SJ.