Table 3.
Standard coagulation assays
| Time point | INR (IQR) | aPTT (IQR) | Fibrinogen (IQR) | Platelets (IQR) |
|---|---|---|---|---|
| (Ref range 0.8–1.2) | (Ref range 26–36 s) | (Ref range 200–450 mg/dl) | (Ref range 150–400 k/cu mm) | |
| Pre-operative | 1.0 (1.0, 1.1) | 30.1 (27.8, 32.3) | 412 (310, 468) | 184 (161, 256) |
| Post-operative | 1.2 (1.2, 1.3)a | 29.1 (26.7, 31.1)b | 294 (230, 347)a | 183 (139, 262) |
| POD #1 | 1.4 (1.2, 1.4)a | 30.0 (27.6, 31.7) | 294 (255, 367)a | 165 (132, 214)a |
| POD #3 | 1.4 (1.3, 1.5)a | 34.1 (32.5, 36.3)a | 451 (314, 540)b | 134 (93, 192)a |
| POD #5 | 1.3 (1.2, 1.4)a | 32.9 (30.9, 37.1)b | 448 (403, 552)b | 176 (115, 214)a |
International normalized ratio (INR) rose significantly after a hepatectomy. Activated partial thromboplastin time (aPTT) remained within normal limits. Fibrinogen decreased dramatically, and then rose beyond pre-operative values. Platelets decreased post-operatively, but trended towards recovery at the end of the study.
IQR, interquartile range; POD, post-operative day.
a
P < 0.01.
b
P < 0.05.