Table 2.

Morbidity, mortality and survival after an elective a total pancreatectomy (TP) – main published series

Author	Period of time	Aetiologies									Mortality rate (%)	Morbidity rate (%)	Diabetes	Survival rates
		Total	Ductal carcinoma	Invasive IPMN	Non-invasive IPMN	Chronic Pancreatitis	Endocrine tumor	Renal cancer metastases	Other malignant	Other benign
Casadei et al.35	2006–2009	20	7	7	1	1	2	2			5%	25%, of which: -hemorrhage=3 -biliary leakage=1	- No death related to diabetes - 23% readmissions for glycemic control	- Ductal carcinoma: 3-y: 25% - Others: 3-y: 90%; 5-y: 70%
Muller et al.13	2001–2006	124	67	10	8	11	10	8	6	4	4.8%	24% surgical 14.5% medical	- No death related to diabetes - 8.3% readmissions for diabetes control	- Malignant disease: 3-y: 37%a - Benign disease: 3-y: 88%a
Billings et al.15	1985–2002	99	33	17	9	20			20		5%	32%	3 deaths owing to hypoglycemia	- Malignant disease: 5-y: 34%b - Benign disease: 5y: 84%b
Schmidt et al.21	1992–2006	33	33 (all R0)								6.1%	48%	–	3-y: 34% 5-y: 14%
Crippa et al.8	1996–2008	65	19	18	13	1	6	6	1	1	0	38.5%, of which: -hemorrhage =3 -biliary leakage=1	No death owing to hypoglycemia	- All patients: 5-y: 71% - Ductal carcinoma: 3-y: 38%; 5-y: 0% - Invasive IPMN: 3-y: 56%; 5-y: 45%
Reddy et al.22	1970–2007	100	100								8%	≈68%	–	3-y: 27% 5-y: 19%
Stauffer et al.26	2002–2008	47	10	10	21	2	1	1	1	1	2%	37%	23/46 living patients were readmitted after discharge	3-y survival: - All patients: 65% - Ductal carcinoma: 34%: - Invasive IPMN: 49% - Non-invasive IPMN: 95%
Present study	1993–2010	56	4	28	11	1	6	2	1	3	3.6%	45%	−1 death owing to hypoglycemia −1 death owing to ketoacidosis	- All patients: 3-y = 62%, 5-y = 55% - Invasive IPMN: 3-y = 40%, 5-y = 22% - Non-invasive IPMN: 3- and 5-y = 90%

^aIncluding other patients with salvage TP.

^bExcept patients who died in the postoperative period.