Table 1.
Base case | Range | Reference | |
---|---|---|---|
Probability variables | |||
Fertilization rates | |||
Failed fertilization with conventional IVF | 0.084 | 0.084–0.227 | text, 3–6 |
Failed fertilization with ICSI | 0.013 | 0–0.036 | text, 3–6 |
Poor fertilization with conventional IVF | 0.078 | NA | text |
Poor fertilization with conventional IVF and ICSI | 0.019 | NA | text |
Live birth rates | |||
IVF for unexplained infertility, aged <35 y | 0.423 | 0.41–0.436 | 14 |
Frozen ET for unexplained infertility, aged <35 y | 0.365 | NA | 14 |
First donor sperm IUI cycle after ICSI failure | 0.276 | NA | 14 |
Cost variables | |||
IVF | 13,842 | 6,920–27,685 | 20, 21 |
ICSI | 1,763 | 1,141–4,280 | 22 |
Embryo cryopreservation | 788 | 393–1,578 | 20 |
Frozen ET cycle | 6,313 | 3,155–12,626 | 20 |
Donor insemination | 1,788 | 1,114–3,607 | 22 |
Note: Cost variables are presented in 2012 US dollars. ICSI = intracytoplasmic sperm injection; NA = not available.
Vitek. Cost-effectiveness analysis of split IVF-ICSI.