Glucocorticoids reduce bone turnover. a) Relationship between the cumulative dose of prednisone and activation frequency in 53 patients after renal transplantation. Coefficient of correlation = 0.43, P < 0.05. b) Relationship between cumulative dose of prednisone and BV/TV in 53 patients after renal transplantation. Coefficient of correlation = 0.54, P < 0.05. Abbreviation: BV/TV, bone volume fraction of total tissue volume. Permission obtained from American Society of Nephrology © Monier-Faugere, M. C. et al. High prevalence of low bone turnover and occurrence of osteomalacia after kidney transplantation. J. A. Soc. Nephrol. 11, 1093-1099 (2000).