Table 3.
Univariable | Multivariable | ||||||
---|---|---|---|---|---|---|---|
HR | p‐Value | 95% CI | HR | p‐Value | 95% CI | ||
Nevus count | >50 | 0.47 | 0.03 | 0.24–0.93 | 0.43 | 0.02 | 0.21–0.89 |
Age | Linear | 1.03 | <0.001 | 1.02–1.05 | 1.02 | 0.02 | 1.00–1.04 |
Breslow thickness (mm) | 1.15 | <0.001 | 1.10–1.19 | 1.07 | 0.02 | 1.01–1.14 | |
Sex | (Male vs. female) | 1.76 | 0.02 | 1.10–2.81 | 1.60 | 0.07 | 0.96–2.65 |
Site of primary | Head and neck | 1 | 1 | ||||
Trunk | 0.31 | <0.001 | 0.16–0.56 | 0.23 | <0.001 | 0.12–0.44 | |
Limbs | 0.45 | 0.01 | 0.25–0.81 | 0.46 | 0.01 | 0.25–0.84 | |
The presence of ulceration | (Yes vs. no) | 2.90 | <0.001 | 1.85–4.53 | 1.30 | 0.29 | 0.79–2.14 |
Tumor mitotic rate | (≥5 vs. <5) | 4.14 | 0.000 | 2.62–6.53 | 3.00 | 0.000 | 1.81–4.97 |
SLN status | Positive vs. negative | 4.41 | <0.001 | 3.38–5.75 | 3.72 | <0.001 | 2.29–6.04 |
Countries | United Kingdom | 1 | 1 | ||||
Spain | 1.20 | 0.53 | 0.67–2.14 | 1.10 | 0.76 | 0.59–2.04 |