Table 3. Results of Real-Time PCR analysis for inflammatory gene.
| Abbreviation | the skin and the subcutaneous tissue | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 12h | 1d | 3d | |||||||
| n = 4 | n = 4 | n = 4 | |||||||
| GM-CSF | 7.85 | (2.93~17.41) | ↑* | 1.71 | (1.00~3.49) | 0.60 | (0.34~1.02) | ||
| IFN-γ | 2.06 | (0.76~3.84) | ↑ | 2.26 | (0.79~5.70) | ↑ | 4.93 | (1.96~8.01) | ↑* |
| IL-1α | 1.97 | (0.86~3.75) | 0.34 | (0.17~0.44) | ↓* | 0.33 | (0.25~0.47) | ↓* | |
| IL-1β | 22.24 | (4.88~41.34) | ↑* | 1.28 | (0.65~1.80) | 1.45 | (0.88~2.16) | ||
| IL-1Ra | 3.98 | (2.04~6.88) | ↑* | 0.73 | (0.59~1.03) | 0.54 | (0.44~0.59) | ||
| IL-2 | 0.64 | (0.16~1.34) | 0.40 | (0.11~0.69) | ↓ | 0.17 | (0.08~0.28) | ↓ | |
| IL-6 | 38.78 | (26.26~66.03) | ↑* | 10.06 | (6.85~12.76) | ↑* | 2.52 | (1.12~4.53) | ↑ |
| IL-10 | 4.36 | (2.23~5.59) | ↑* | 3.95 | (2.46~6.29) | ↑* | 1.07 | (0.71~1.63) | |
| MMP-3 | 9.01 | (3.36~16.10) | ↑* | 12.54 | (5.70~19.05) | ↑* | 2.61 | (1.82~3.42) | ↑* |
| TGF-β1 | 1.13 | (0.56~1.86) | 0.59 | (0.59~1.19) | 1.26 | (1.03~1.74) | |||
| TIMP-1 | 2.93 | (2.00~4.02) | ↑* | 3.35 | (2.07~4.14) | ↑* | 1.54 | (1.27~1.68) | * |
| TNF-α | 17.96 | (3.07~39.39) | ↑* | 1.36 | (0.90~1.64) | 0.77 | (0.59~1.16) | ||
RNAs from the skin and the subcutaneous tissue were analyzed. Values were described as fold changes (minimum value ~ maximum value). Up-pointing arrows: up-regulated over twice, down-pointing arrows: down-regulated less than half.
* p<0.05.