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. 2015 Jul 16;4:355. doi: 10.1186/s40064-015-1021-8

Figure 3.

Figure 3

Expression of Oprd1 gene in the striatum (a), hypothalamus (b), and PAG (c) in OVX female rats. The W group remained undisturbed. The SS group received saline solution 54 and 2 h before the experiments. The SM group received saline 54 h and 3.5 mg/kg morphine 2 h before the experiments. The ES group received estrogen (50 µg/kg, i.p.) 54 h before testing and saline 2 h before the experiments. The EM group received estrogen (50 µg/kg, i.p.) 54 h before testing and 3.5 mg/kg morphine 2 h before the experiments. *p < 0.05, compared with SS group. The data are expressed as mean ± SEM (ANOVA followed by Tukey’s multiple-comparison test).