Table 5.

Comparison of AST and ALT values in different administration routes

Administration	Enzyme activity (IU/L)
	Day 1	Day 7	Day 14	Day 28	Day 42	Day 56	Day 71
AST
Intravenous	801 ± 255	1,390 ± 492	644 ± 200	281 ± 81
Intrapleural			214 ± 65	219 ± 38	202 ± 30	173 ± 23	169 ± 31
ALT
Intravenous	356 ± 112	1,881 ± 648	1,031 ± 320	223 ± 62
Intrapleural			361 ± 172	180 ± 63	205 ± 55	76 ± 12	65 ± 14

Data show average and SE values (n = 5). CrlJ:CD1 mice injected with Ad-NK4 were 5-week old male. Data of untreated CrlJ:CD1 male mice at 11-week old (Japan Charles river, Japan) as follows.

AST, 76 ± 11 IU/l; ALT, 32 ± 7 IU/l.