Table 4. Analysis of Leukocyte Cell Types Present in the Whole Blood of Control and Amphetamine Treated Rats.
Cell Type | Control b | AMPH a | Reference for Charles River Control b |
---|---|---|---|
Total Leukocytes (WBC) | 10.60 ± 1.00 | 9.93 ± 1.03 | 10.83 ± 3.84 |
Lymphocytes (T- and B-cells) | 7.65 ± 0.69 | 5.55 ± 0.57* | 6.72 ± 2.53 |
Neutrophils | 2.51 ± 0.49 | 3.57 ± 0.48* | 3.31 ± 1.67 |
Monocytes | 0.37 ± 0.06 | 0.90 ± 0.14* | 0.67 ± 0.33 |
Eosinophils | 0.04 ± 0.01 | 0.03 ± 0.01 | 0.13 ± 0.13 |
Basophils | 0.02 ± 0.00 | 0.06 ± 0.02 | 0.03 ± 0.04 |
Erythrocytes (RBC) | 7.83 ± 0.34 | 8.44 ± 0.24 | 7.6 ± 1.17 |
a Values for the total and various cell types of leukocytes are measured in thousands (103) per cubic mm of blood and erythrocyte levels are given in millions (106) per cubic mm of blood. Reported values represent mean ± SEM for blood samples collected from 16 control and 16 AMPH animals.
b Reference values for the total and various cell types of leukocytes and RBCs for 56 to 70 day old adult male Charles River Crl:CD(SD) rats were obtained from http://www.criver.com/files/pdfs/rms/cd/rm_rm_d_cd_rat.aspx. The mean ± standard deviation levels are given.
*p < 0.05; Mann-Whitney U test.