Table 1. Overview of study design for the MethylMiner versus MethylCap comparison and number of reads in each condition.
Individual | Technical Duplicate | MBD-capture Kit | Captured DNA (ng) | Total Reads | % Mapped Reads | % Used Reads |
---|---|---|---|---|---|---|
A | 1 | MethylMiner | 284 | 32,786,373 | 71.9 | 28.2 |
A | 2 | MethylMiner | 273 | 43,543,509 | 71.9 | 25.1 |
A | 1 | MethylCap | 77 | 32,213,938 | 72.9 | 29.9 |
A | 2 | MethylCap | 85 | 23,883,650 | 74.0 | 30.3 |
B | 1 | MethylMiner | 317 | 48,397,266 | 72.2 | 32.2 |
B | 2 | MethylMiner | 312 | 42,712,240 | 70.5 | 34.0 |
B | 1 | MethylCap | 115 | 31,148,759 | 74.0 | 34.9 |
B | 2 | MethylCap | 106 | 29,959,582 | 72.9 | 31.5 |