Table 3. Chosen SNVs from selected KTCN association studies involving experiments indicating especially CCT genes.
| Gene | rs number | Allel | 1000 Genomes ALL Freq | Freq control | Freq cases | Population | References |
|---|---|---|---|---|---|---|---|
| BANPZNF469* | rs9938149 | A | 0.743 | 0.620 | 0.720 | Australian—European descent | Sahebjada et al., 2013 |
| COL5A1* | rs1536482 | A | 0.353 | 0.310 | 0.370 | Caucasian, Hispanic | Li et al., 2013 |
| COL5A1 | rs1536482 | A | 0.353 | 0.390 | 0.280 | USA–Caucasian | Li et al., 2013 |
| COL5A1 | rs1536482 | A | 0.353 | 0.360 | 0.420 | USA–Caucasian | Li et al., 2013 |
| COL5A1 | rs7044529 | T | 0.189 | 0.120 | 0.220 | Caucasian, Hispanic | Li et al., 2013 |
| COL5A1 | rs7044529 | T | 0.189 | 0.140 | 0.170 | USA–Caucasian | Li et al., 2013 |
| COL5A1 | rs7044529 | T | 0.189 | 0.150 | 0.160 | USA–Caucasian | Li et al., 2013 |
| HGF | rs2286194 | A | 0.198 | 0.209 | 0.131 | Australian—European descent | Sahebjada et al., 2014 |
| HGF | rs5745752 | A | 0.258 | 0.291 | 0.409 | Australian—European descent | Sahebjada et al., 2014 |
| IL1A | rs2071376 | A | 0.578 | 0.249 | 0.277 | Japan | Mikami et al., 2013 |
| IL1B | rs1143627 | T | 0.519 | 0.537 | 0.607 | Japan | Mikami et al., 2013 |
| IL1B | rs16944 | C | 0.534 | 0.537 | 0.607 | Japan | Mikami et al., 2013 |
| LOX | rs10519694 | T | 0.149 | 0.290 | 0.200 | Caucasian, Hispanic | Bykhovskaya et al., 2012 |
| LOX | rs10519694 | T | 0.149 | 0.260 | 0.180 | USA–Caucasian | Bykhovskaya et al., 2012 |
| LOX | rs10519694 | T | 0.149 | 0.220 | 0.200 | USA–Caucasian | Bykhovskaya et al., 2012 |
| LOX | rs2956540 | G | 0.648 | 0.540 | 0.400 | Caucasian, Hispanic | Bykhovskaya et al., 2012 |
| LOX | rs2956540 | G | 0.648 | 0.440 | 0.360 | USA–Caucasian | Bykhovskaya et al., 2012 |
| LOX | rs2956540 | G | 0.648 | 0.440 | 0.360 | USA–Caucasian | Bykhovskaya et al., 2012 |
| MPDZ-NF1B* | rs1324183 | A | 0.217 | 0.190 | 0.290 | Australian—European descent | Sahebjada et al., 2013 |
| RAB3GAP1 | rs1428642 | A | 0.514 | 0.460 | 0.500 | Caucasian, Hispanic | Li et al., 2012 |
| RAB3GAP1 | rs1428642 | A | 0.514 | 0.450 | 0.330 | USA–Caucasian | Li et al., 2012 |
| RAB3GAP1 | rs1428642 | A | 0.514 | 0.430 | 0.420 | USA–Caucasian | Li et al., 2012 |
| RAB3GAP1 | rs4954218 | G | 0.098 | 0.306 | 0.251 | Australian Caucasian | Bae et al., 2013 |
| RAB3GAP1 | rs4954218 | G | 0.098 | 0.220 | 0.160 | Caucasian, Hispanic | Li et al., 2012 |
| RAB3GAP1 | rs4954218 | G | 0.098 | 0.250 | 0.140 | USA–Caucasian | Li et al., 2012 |
| RAB3GAP1 | rs4954218 | G | 0.098 | 0.230 | 0.170 | USA–Caucasian | Li et al., 2012 |
| RAB3GAP1 | rs6442925 | T | 0.157 | 0.220 | 0.240 | Caucasian, Hispanic | Li et al., 2012 |
| RAB3GAP1 | rs6442925 | T | 0.157 | 0.150 | 0.250 | USA–Caucasian | Li et al., 2012 |
| RAB3GAP1 | rs6442925 | T | 0.157 | 0.180 | 0.170 | USA–Caucasian | Li et al., 2012 |
| TF | rs8177178 | A | 0.360 | 0.295 | 0.375 | Polish | Wojcik et al., 2013 |
* Genes associated with KTCN and corneal thickness