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. 2015 Aug 1;116:123–134. doi: 10.1016/j.neuroimage.2015.05.012

Table S6.

Summary of main effects and interactions of the frequency range, sleep dependent and circadian factors on the studied SW parameters as measured during the forced desynchrony.

SW parameter Segment Effect DF F value P value Cohen's f2
Incidence Frequency range 1 22.3 < 0.0001**** 0.25M
Sleep dependent 2 1119.14 < 0.0001**** 18.45L
Circadian 5 43 < 0.0001**** 0.63L
Frequency range ∗ Circadian 5 0.16 ns
Frequency range ∗ Sleep dependent 2 2.41 ns
Sleep dependent ∗ Circadian 10 7.08 < 0.0001**** 0.15S
Amplitude Frequency range 1 17.16 < 0.0001**** 0.18M
Sleep dependent 2 553.75 < 0.0001**** 9.27L
Circadian 5 32.64 < 0.0001**** 0.59L
Frequency range ∗ Circadian 5 0.07 ns
Frequency range ∗ Sleep dependent 2 0.37 ns
Sleep dependent ∗ Circadian 10 5.04 < 0.0001**** 0.11S
Duration Initial Frequency range 1 186 < 0.0001**** 1.63L
Sleep dependent 2 45.6 < 0.0001**** 0.68L
Circadian 5 9.48 < 0.0001**** 0.15S
Frequency range ∗ Circadian 5 0.28 ns
Frequency range ∗ Sleep dependent 2 0.64 ns
Sleep dependent ∗ Circadian 10 5.46 < 0.0001**** 0.11S
Final Frequency range 1 118.15 < 0.0001**** 1.13L
Sleep dependent 2 12.52 < 0.0001**** 0.21M
Circadian 5 20.02 < 0.0001**** 0.39L
Frequency range ∗ Circadian 5 0.34 ns
Frequency range ∗ Sleep dependent 2 0.27 ns
Sleep dependent ∗ Circadian 10 3.77 < 0.0001**** 0.08S
Mean slope Initial Frequency range 1 147.19 < 0.0001**** 1.48L
Sleep dependent 2 165.91 < 0.0001**** 2.61L
Circadian 5 40.7 < 0.0001**** 0.63L
Frequency range ∗ Circadian 5 0.37 ns
Frequency range ∗ Sleep dependent 2 0.43 ns
Sleep dependent ∗ Circadian 10 3.5 0.0002*** 0.07S
Final Frequency range 1 82.28 < 0.0001**** 0.87L
Sleep dependent 2 185.93 < 0.0001**** 3.38L
Circadian 5 46.71 < 0.0001**** 1.03L
Frequency range ∗ Circadian 5 0.5 ns
Frequency range ∗ Sleep dependent 2 0.14 ns
Sleep dependent ∗ Circadian 10 2.24 0.015 0.05S
Maximum slope Initial Frequency range 1 71.03 < 0.0001**** 0.77L
Sleep dependent 2 284.52 < 0.0001**** 4.45L
Circadian 5 38.03 < 0.0001**** 0.55L
Frequency range ∗ Circadian 5 0.11 ns
Frequency range ∗ Sleep dependent 2 0.12 ns
Sleep dependent ∗ Circadian 10 3.53 0.0002*** 0.07S
Final Frequency range 1 56.81 < 0.0001**** 0.62L
Sleep dependent 2 381.97 < 0.0001**** 6.58L
Circadian 5 57.46 < 0.0001**** 1.07L
Frequency range ∗ Circadian 5 0.2 ns
Frequency range ∗ Sleep dependent 2 0.09 ns
Sleep dependent ∗ Circadian 10 2.56 0.0051 0.06S

We assessed the effect of the frequency band-width used for SW detection. All SW parameters for the frequency band 0.5–2 Hz and 0.5–4 Hz were analysed in the same mixed model adding the factor ‘frequency range’. We found this factor to have a significant effect on most SW parameters, however, the sleep-dependent and circadian main effects remained significant and were not modulated by the frequency range used for the analysis.

We assessed the effect of the frequency band-width used for SW detection. All SW parameters for the frequency band 0.5–2 Hz and 0.5–4 Hz were analysed in the same mixed model adding the factor ‘frequency range’. We found this factor to have a significant effect on most SW parameters, however, the sleep-dependent and circadian main effects remained significant and were not modulated by the frequency range used for the analysis.

Results for negative half-waves are presented. The frequency range factor comprises the 0.5–2 Hz and the 0.5–4 Hz band-width. The sleep-dependent factor includes thirds of the total sleep period (9 h 20 m). The circadian factor comprises 6 ∗ 60° bins. The Segment variable indicates the descending (initial) or the ascending (final) phase of the slow wave (SW) negative half waves. Degree of freedom (DF), F values, P values, effect size (Cohen's f2) of main effects, and interactions are indicated for each studied variables as returned from mixed model analyses of variances (***P < .0005 and ****P < .0001). Superscripts following effect size values indicate the magnitude of the effects size [small(S): 0.02–0.15, medium (M): 0.15–0.35, large (L): > 0.35]. P values and effect sizes for non-significant effects are not indicated. Non-significant trends (< 0.05) are indicated.