Table 1.
Serum enzyme activities and biochemical parameters in control and treated groups
| Parameters | Experimental groups | |||||
|---|---|---|---|---|---|---|
| Control | DAS | Curcumin | TI | TI-DAS | TI-curcumin | |
| AST (U/L) | 23.8a ± 1.28 | 24.1a ± 1.17 | 22.8a ± 1.46 | 58.9b ± 1.96 | 36.1c ± 1.76 | 28.9a ± 1.97 |
| ALT (U/L) | 29.9a ± 2.23 | 28.4a ± 1.426 | 27.4a ± 1.40 | 84.4b ± 3.28 | 52.1c ± 1.23 | 44.0c ± 1.58 |
| ALP (U/L) | 74.3a ± 3.09 | 72.3a ± 2.95 | 70.9a ± 2.29 | 107b ± 2.74 | 95.5c ± 1.32 | 85.4d ± 2.17 |
| LDH (U/L) | 46.9a ± 1.43 | 41.0ac ± 2.38 | 38.6c ± 1.08 | 65.8b ± 1.10 | 56.0d ± 0.96 | 53.9d ± 1.60 |
| γ-GT (U/L) | 36.3a ± 1.81 | 33.0a ± 1.25 | 31.8a ± 0.92 | 155b ± 5.55 | 86.5c ± 2.54 | 64.8d ± 3.29 |
| Cholesterol (mg/dl) | 67.1a ± 1.26 | 61.1c ± 1.04 | 59.5c ± 1.05 | 81.6b ± 0.78 | 70.8a ± 1.47 | 67.0a ± 2.16 |
| T protein (g/dl) | 8.25a ± 0.17 | 8.33a ± 0.13 | 8.24a ± 0.17 | 6.46b ± 0.12 | 7.23c ± 0.09 | 7.51c ± 0.14 |
| T bilirubin (mg/dl) | 1.48ac ± 0.03 | 1.50ac ± 0.02 | 1.41c ± 0.03 | 1.76b ± 0.03 | 1.53a ± 0.02 | 1.44ac ± 0.03 |
Data are expressed as means ± SE; n=8.
TI; Thallium acetate, DAS; Diallyl sulfide, AST; Aspartate aminotransferase, ALT; Alanine aminotransferase, ALP; Alkaline phosphatase, LDH; Lactic dehydrogenase, γ-GT; Gamma glutamyltransferase, T protein; Total protein and T bilirubin; Total bilirubin.
Within the same row, different letters indicate statistical significance at P<0.05.