Table 3.
Liver oxidative stress (OS) marker and antioxidant parameters in control and treated groups
Parameters | Experimental groups | |||||
---|---|---|---|---|---|---|
Control | DAS | Curcumin | TI | TI-DAS | TI-curcumin | |
MDA (nmol/g) | 30.0a ± 1.71 | 29.6a ± 1.16 | 28.1a ± 1.08 | 65.5b ± 1.78 | 51.0c ± 1.35 | 45.0d ± 1.45 |
GSH (mg/g) | 55.9a ± 1.49 | 56.3a ± 0.75 | 56.9a ± 1.30 | 38.1b ± 1.19 | 45.8c ± 1.16 | 46.8c ± 1.73 |
SOD (U/g) | 759.25a ± 17.2 | 788.5a ± 15.4 | 806.63a ± 24.4 | 321.6b ± 18.9 | 653.8c ± 9.1 | 696.1c ± 23.6 |
CAT (U/g) | 0.77a ± 0.03 | 0.79a ± 0.03 | 0.82a ± 0.03 | 0.49b ± 0.01 | 0.56c ± 0.02 | 0.65b ± 0.02 |
TAC (mmol/g) | 46.4a ± 1.22 | 47.4ac ± 1.40 | 50.3c ± 0.65 | 36.1b ± 0.69 | 44.9a ± 1.03 | 46.1a ± 0.81 |
Data are expressed as means ± SE; n=8.
TI; Thallium acetate, DAS; Diallyl sulfide, MDA; Malondialdehyde, GSH; Reduced glutathione, SOD; Superoxide dismutase, CAT; Catalase and TAC; Total antioxidant capacity.
Within the same row, different letters indicate statistical significance at P<0.05.