Table 1.
Characteristics in women with fractures and controls
| Cases (n = 211) | Controls (n = 232) | p value | |
|---|---|---|---|
| Age (years) | 68.4 (7.7) | 68.3 (6.7) | 0.94 |
| Height (cm) | 162.7 (6.1) | 161.2 (6.6) | 0.01 |
| Weight (kg) | 68.9 (10.5) | 70.0 (10.8) | 0.28 |
| Total Hip aBMD (mg/cm2) | 854 (113) | 930 (115) | <0.001 |
| Femoral neck (FN) aBMD (mg/cm2) | 794 (100) | 860 (112) | <0.001 |
| Have normal FN aBMD, n (%) | 47 (22.3) | 112 (48.3) | <0.001 |
| Have osteopenia, n (%) | 146 (69.2) | 109 (47.0) | <0.001 |
| Have osteoporosis, n (%) | 18 (8.5) | 11 (4.7) | 0.11 |
| FRAX score with FN aBMD (%) | 15.1 (8.4) | 10.8 (4.9) | <0.001 |
| FRAX score without FN aBMD (%) | 16.3 (10.2) | 12.7 (6.2) | <0.001 |
| Femoral subtrochanteric parameters | |||
| Total bone vBMD (mg HA/cm3) | 684 (113) | 750 (90.0) | <0.001 |
| Cortical vBMD (mg HA/cm3) | 1025 (72.6) | 1059 (56.6) | <0.001 |
| Cortical porosity (%) | 43.8 (4.3) | 41.7 (3.4) | <0.001 |
| Trabecular bone volume/tissue volume (%) | 0.27 (0.02) | 0.27 (0.02) | 0.81 |
| Alcohol intake (drinks/week) | 2.7 (2.5) | 2.8 (2.3) | 0.80 |
| Currently smoking, n (%) | 29 (13.7) | 24 (10.3) | 0.26 |
| Physical activity (h/week) | 2.6 (1.6) | 2.5 (1.7) | 0.42 |
| History of previous fracture, n (%) | 54 (25.6) | 0 | |
| Parental history of hip fracture, n (%) | 34 (16.1) | 37 (16.0) | 0.96 |
| Self-reported excellent/good health status, n (%) | 147 (70.3) | 165 (71.1) | 0.86 |
| Rheumatoid arthritis, n (%) | 11 (5.2) | 8 (3.5) | 0.36 |
| Oral corticosteroid use, n (%) | 8 (3.8) | 2 (0.9) | 0.04 |
| Take calcium supplements, n (%) | 44 (20.9) | 28 (12.1) | 0.01 |
| Take supplements of vitamin D, n (%) | 163 (77.3) | 166 (71.6) | 0.17 |
Data are mean (SD) or number (%)
p values are adjusted for age using analysis of variance
FRAX Fracture Risk Assessment Tool for calculation of the 10-year probability of a major osteoporotic fracture, aBMD areal bone mineral density, vBMD volumetric bone mineral density