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Cytokines in immunosuppressed BALB/c mouse lung after pre-exposure prophylaxis with AP at day + 8 after infection:
(A) For IFN-γ, no differences were seen.
(B) TNF-α at day + 8 showed a small increase when compared to day + 2 after infection in mice with AP pre-exposure prophylaxis (n = 4 mice/time point). AF (d + 2) = 187,800 ± 61,500 copies/105 copies HPRT; AF + AP (d + 2) = 66,270 ± 2730 copies/105 copies HPRT; AF + AP (d + 8) = 80,900 ± 7550 copies/105 copies HPRT.
