Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 16;5:10457. doi: 10.1038/srep10457

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Effects of oral administration of AP-PG on liver injury caused by HFD (A) ALT activity in the serum of the mice.(B-D) Expression of Hydroxymethylglutaryl-CoA (HMG-CoA) reductase (HMGR; B), HMG-CoA synthase (HMGS; C), and cholesterol 7 alpha-hydroxylase (CYP7A1; D) mRNAs in the liver quantified using real-time RT-PCR. Data represent relative expression values compared with the NC control after normalization with glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mRNA expression. (E) Feces were collected from mice at the time point indicated in the Figure, and the amounts of fecal bile acid were measured as described in Method section. Data represent relative bile acid amounts compared with the control. Error bars indicate standard deviations. NC: normal control diet. HFD: high-fat diet. Single asterisk (*), double asterisks (**), and triple asterisks (***) indicate statistically significant differences (p < 0.05, p < 0.01, and p < 0.005 respectively). n.s.: not significant.