Fig. 2.

PIP peptide 250 can enhance the uptake of larger solutes than peptide 640 in vitro. Cumulative apical to basal transport of fluorescent dextran across Caco-2 monolayers induced by the apical application of designated concentrations of PIP peptide 250 or 640. (A) 4 kDa dextran transport induced by peptides 250 and 640. (B) 70 kDa dextran transport induced by peptides 250 and 640. PBS added to the apical compartment served as control. Data are means ± SD, n = 6 for control and n = 5 for all peptide treatment groups. * Significantly different from control with two-tailed, un-paired t-test.