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. 2015 Jun 18;58(6):1040–1052. doi: 10.1016/j.molcel.2015.04.018

Figure 2.

Figure 2

CGRPmut and AM Interactions with Their Receptor ECD Complexes

(A and C) The peptide-bound structures viewed with the receptor complexes in molecular surface representation and the peptides as cartoons with side chains as sticks.

(B and D) Detailed views with the receptors in cartoon representation and selected receptor residues and the peptides as sticks. Red dashes are hydrogen bonds. Peptide residues are labeled in (A) and (C) and receptor residues are labeled in (B) and (D). In (B), CGRPmut residues F27 and V28 are shown as lines for visualization of the CGRPmut T30-CLR D94 interaction. See also Tables S1 and S2.