Table 1.
Baseline characteristics of study participants*
| Baseline Characteristics | Noncases (n=4940) |
Cardiovascular Disease Cases (n=516) |
p-value† |
|---|---|---|---|
| Age, y | 62 ± 10 | 68 ± 10 | <0.001 |
| Male | 2280 (46%) | 315 (61%) | <0.001 |
| Race/ethnicity | |||
| Black | 1264 (26%) | 135 (26%) | 0.001 |
| Chinese | 677 (14%) | 41 (8%) | |
| Hispanic | 1113 (22%) | 110 (21%) | |
| White | 1886 (38%) | 230 (45%) | |
| Body mass index, kg/m2 | 28 ± 5 | 29 ± 5 | 0.054 |
| Systolic blood pressure, mm Hg | 125 ± 21 | 136 ± 23 | <0.001 |
| Diastolic blood pressure, mm Hg | 72 ± 10 | 74 ± 11 | <0.001 |
| Cholesterol, mg/dl | |||
| Total | 194 ± 36 | 196 ± 37 | 0.461 |
| LDL | 117 ± 31 | 120 ± 33 | 0.063 |
| HDL | 52 ± 15 | 48 ± 14 | <0.001 |
| Cigarette smoking | |||
| Current | 601 (12%) | 73 (14%) | 0.005 |
| Former | 1784 (36%) | 215 (42%) | |
| Never | 2539 (52%) | 227 (44%) | |
| Diabetes | 565 (11%) | 116 (22%) | <0.001 |
| Statin use | 697 (14%) | 102 (20%) | <0.001 |
| Anti-hypertensive use | 1726 (35%) | 279 (54%) | <0.001 |
| C-reactive protein, mg/L | 3.7 ± 6 | 4.2 ± 5.9 | 0.093 |
| Lp-PLA2 activity, nmol/min/ml | 148 ± 37 | 158 ± 36 | <0.001 |
| Lp-PLA2 mass, ng/ml | 177 ± 42 | 186 ± 43 | <0.001 |
*
Values are means ± SD or numbers (percentages of total).
†
p values were obtained using t-tests for continuous variables and chi-square test for categorical variables