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. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: Atherosclerosis. 2015 May 16;241(1):176–182. doi: 10.1016/j.atherosclerosis.2015.05.006

Table 4.

Association of Lp-PLA₂ activity and risk of incident cardiovascular disease stratified by race/ethnicity^*

	Cardiovascular Disease		Coronary Heart Disease		Coronary Heart Disease - Hard
	Hazard Ratio^† (95% CI)	p-value	Hazard Ratio (95% CI)	p-value	Hazard Ratio (95% CI)	p-value
Race/Ethnicity^‡
Black	1.17 (0.97, 1.40)	0.10	1.27 (1.02, 1.59)	0.03	1.33 (1.01, 1.75)	0.04
Chinese	0.95 (0.71, 1.28)	0.74	0.90 (0.64, 1.26)	0.53	0.79 (0.50, 1.26)	0.32
Hispanic	1.41 (1.16, 1.71)	0.001	1.52 (1.21, 1.92)	<0.001	1.49 (1.13, 1.95)	0.004
White	1.25 (1.09, 1.44)	0.001	1.26 (1.07, 1.48)	0.007	1.31 (1.05, 1.62)	0.015

^*

Mean Lp-PLA₂ activity values (mmol/min/mL) according to race/ethnicity: Black 137, Chinese 152, Hispanic 152, White 156

^†

Cox Proportional Hazard ratios adjusted for age and gender and expressed per 1 standard deviation increment.

^‡

p-value for interaction by race/ethnicity for Lp-PLA₂ activity and the endpoints of CVD, CHD, and ‘hard’ CHD are 0.16, 0.06, and 0.07 respectively.