Fig. 11.

Overview of how often the 20 amino acids were involved in the POM–protein binding based on the PDB related structures from Table 1. The ordinate indicates the number and the abscissa the kind of amino acids present in the interactions. Amino acids are categorized in basic (blue bars), acidic (red bars), polar but uncharged (dark yellow bars) and unpolar (green bars) ones. In the upper right of the figure the division into the four categories is displayed as a pie chart with the same coloring as the bar graph. All 30 structures from Table 1 were analyzed with the molecular visualization system PyMOL [107] and the model building and validation system Coot [108] with respect to POM–protein interactions. POM–protein interactions with interaction distances up to 4.5 Å were taken into account. Overall, 241 residues are involved in these interactions and subsequently categorized as shown above.