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. 2015 Sep 1;299:22–38. doi: 10.1016/j.ccr.2015.03.018

Table 2.

PDB entries containing POMs which are not modeled in the protein structure.

PDB entry Protein (organism) Number of metal atoms Origin of POM Purpose of POM use POM impact on crystallization/structure Ref.
4PE5 NMDA receptor ion channel (R. norvegicus) 12 W probably [H2W12O40]6− Soaking in Na6[H2W12O40] Heavy atom derivative for phasing. Improvement of crystal quality [99]
3FYH DNA repair and recombination protein RadA (M. voltae) 12 W probably [H2W12O40]6− Added as Na6[H2W12O40] Rad inhibitor Stabilization of the inactive form [100]
2G8H RNase H (B. halodurans) 6 V maybe Lindqvist [V6O19]8− Self-assembly in the presence of NaVO3 VO3− as substrate mimic Stabilization of an intermediate conformation [101]