Table 1.
Summary of datasets D1, D2 and D3, containing locus-specific methylation data for colon cancer and adjacent healthy looking tissues, obtained with the array-based platform Illumina Infinium HumanMethylation27 (HM27).
| D1 | D2 | D3 | |
|---|---|---|---|
| GEO ID | GSE25062 | GSE29490 | GSE27130 |
| Origin | Fresh-frozen surgically removed colonic specimens, Groene Hart Hospital, Gouda, The Netherlands or the Ontario Tumor Bank Network (The Ontario Institute for Cancer Research, Ontario, Canada). | Fresh-frozen surgically removed colonic specimens, Department of Pathology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. | Fresh-frozen colonic specimens from patients treated at Samsung Med- ical Center (Seoul, Korea). |
| DNA extraction method | TRIzol Reagent (Invitrogen) | Puregene Core kit (Qiagen) | DNeasy Tissue kit (Qiagen) |
| Cell lines | 0 | 0 | 12 |
| Tumours | 125 | 24 | 118 |
| Adjacent tissue | 29 | 24 | 118 |
| No. loci selected for clustering | 48 | 24 | 43 |