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. 2015 Jul 16;10(7):e0132006. doi: 10.1371/journal.pone.0132006

Table 3. Correlations between the liver iron concentration determined by MRI and iron biomarkers in 212 hemodialysis patients studied (Spearman rank order correlation test).

Overall Cohort (n°1+n°2)(212 patients) Cohort n°1 of 119 patients Cohort n°2 of 93 patients
Parameter Spearman rho [95% confidence interval] P values at test Spearman rho [95% confidence interval] P values at test Spearman rho [95% confidence interval] P values at test
Serum Ferritin (microg/L) 0.52 [0.41 to 0.61] p< 0.0001 0.52 [0.37 to 0.65] p< 0.0001 0.47 [0.29 to 0.62] p< 0.0001
serum iron (micromol/L) 0.22 [0.09 to 0.35] p = 0.0011 0.26 [0.07 to 0.42] p = 0.0048 0.26 [0.05 to 0.44] p = 0.0128
Serum Transferrin (g/L) - 0.34 [-0.46 to -0.21] p< 0.0001 -0.24 [-0.41 to -0.05] p = 0.0131 -0.35 [-0.52 to -0.15] p = 0.0006
Serum solubleTransferrin receptors (sTfR) (mg/L) - 0.12 [-0.27 to 0.02] p = 0.0868 -0.07 [-0.27 to 0.14] p = 0.5249 -0.11 [-0.31 to 0.11] p = 0.3128
TSAT (%) 0.36 [0.24 to 0.48] p< 0.0001 0.37 [0.20 to 0.52] p< 0.0001 0.36 [0.16 to 0.53] p = 0.0004
sTfR/Ferritin ratio - 0.43 [-0.54 to -0.30] p< 0.0001 -0.44 [-0.59 to -0.26] p< 0.0001 -0.36 [-0.53 to −0.16] p = 0.0004
Hepcidin (ng/mL) 0.42 [0.29 to 0.54] p< 0.0001 0.34 [0.14 to 0.51] p = 0.0008 0.42 [0.23 to 0.58] p< 0.0001
Erythrocyte mean corpuscular volume (fL) 0.04 [-0.10 to 0.18] p = 0.5637 0.002 [-0.18 to 0.19] p = 0.99 0.14 [-0.07 to 0.34] p = 0.1774

Data are given as area of the Spearman rho with the [95% confidence interval].