Table 4. Area under the receiver operating characteristics (ROC) curve of iron biomarkers for diagnosis of iron overload (LIC > 50 micromol/g) in 212 hemodialysis patients studied by hepatic MRI.
Overall Cohort (n°1 + n°2)(n = 212) | |
---|---|
Serum iron (micromol/L) | 0.556 [0.466 to 0.645] p = 0.223 |
Serum Transferrin (g/L) | 0.703 [0.623 to 0.783] p< 0.0001 |
Serum Ferritin (microg/L) | 0.767 [0.698 to 0.835] p< 0.0001 |
TSAT (%) | 0.634 [0.552 to 0.715] p = 0.001 |
Serum soluble transferrin receptor (sTfR) (mg/L) | 0.545 [0.455 to 0.636] p = 0.327 |
sTfR/Ferritin ratio | 0.709 [0.629 to 0.789] p< 0.0001 |
Serum Hepcidin (ng/mL) | 0.710 [0.631 to 0.789] p< 0.0001 |
Erythrocyte mean corposcular Volume (fL) | 0.556 [0.464 to 0.648] p = 0.233 |
Data are given as area of the ROC curve with the [95% confidence interval].