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. 2015 Jun 26;94(25):e998. doi: 10.1097/MD.0000000000000998

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Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0

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Representative IHC staining analysis for GLI1, NFATc4, ABLIM3, and FES in PTC from 1 patient in GLI1 group I and 2 patients classified into GLI1 group III (original magnification ×200). In low GLI1 PTC, GLI1, NFATc4, ABLIM3, and FES are barely detected. In high GLI1 PTC, GLI1, and NFATc4 are mainly detected in the nucleus. ABLIM3 and FES are exclusively located in the cytoplasm. FES = feline sarcoma oncogene, GLI1 = glioma-associated oncogene homolog 1, IHC = immunohistochemical, PTC = papillary thyroid cancer.