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. 2015 Jul 16;10(7):e0133485. doi: 10.1371/journal.pone.0133485

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© 2015 Patel et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — A, Representative traces of recovery from fast inactivation measured by first inducing fast inactivation from a holding potential of -100mV with a 20ms step pulse to 0mV and then applying a 20ms test pulse to 0mV subsequent to various recovery times at -70mV. Inset, Protocol used to measure recovery from fast inactivation. B, hNav1.6 (blue circles; n = 17) has a smaller time constant for recovery at -70mV compared to hNav1.1 (black squares; n = 19). C, Maximal fraction recovered from fast inactivation was greater for hNav1.1 at voltage ranging from -90mV to -70mV compared to hNav1.6 (Unpaired t-test, *p < 0.05).