Fig 7. As2O3 specifically increases SIVMAC infectivity in human blood cells.
TE671 cells (A), Jurkat T cells (B), human PBMC (C), or human CD4+ T cells (D) were transduced with two-part, VSV G-pseudotyped HIV-1NL4-3-GFP or SIVMACGFP vectors using a predetermined quantity of virus such that 1% of cells were infected. As2O3 was added 1 hr prior to vector challenge and maintained for 12 hrs post-infection, at the concentrations indicated on the X axis. 48 hrs post-challenge the percentage of GFP-expressing cells was determined. The Y axis shows the fold increase relative to infection without As2O3.