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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Shock. 2015 Aug;44(2):173–180. doi: 10.1097/SHK.0000000000000390

Figure 5. mRNA expression of mitochondrial biogenesis factors and mitochondria abundance in kidney.

Figure 5

A, mRNA expression of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1-α) was significantly elevated in LR+RSV resuscitation group compared to the LR resuscitation only group. However, the mRNA expressions of mitochondrial transcription factor A (TFAM), nuclear respiratory factor (NRF) 1 and 2 were not influenced by RSV supplementation. B, Citrate synthase activity was determined spectrophotometrically based on coenzyme A coupled to 5, 5′-dithiobis-2-nitrobenzoic acid. Citrate synthase activity did not significantly change with Severe Shock or with resuscitative strategy. LR = Lactated Ringer’s solution; RSV = Resveratrol. Values are mean ± SEM. n = 6, *p<0.05 versus Sham; †p<0.05 versus Severe Shock; ‡p<0.05 versus LR Resuscitation.