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. Author manuscript; available in PMC: 2016 Jul 20.
Published in final edited form as: Angew Chem Int Ed Engl. 2015 Jun 10;54(30):8648–8652. doi: 10.1002/anie.201502287

Figure 3.

Figure 3

Dual-channel in vivo fluorescence imaging of cartilage and bone tissues by using C700-OMe and P800SO3− [15] in the same animals. 10 nmol and 1 μmol of C700-OMe and P800SO3− were intravenously injected into 25 g CD-1 mice (top; 0.4 mg kg−1) and 35 kg Yorkshire pigs (bottom; 0.02 mg kg−1), simultaneously, 4 h prior to imaging. All NIR fluorescence images for each condition have identical exposure times and normalizations. Scale bars = 1 cm. Images are representative of n = 3 independent experiments. Pseudo-colored red and green colors were used for 700 nm and 800 nm channel images, respectively, in the color-NIR merged image.