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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Shock. 2015 Aug;44(0 1):63–70. doi: 10.1097/SHK.0000000000000376

Figure 1. COMBAT Biological Sampling Timeline.

Figure 1

Samples are drawn at 11 time points, starting in the field, immediately before randomization and the administration of the initial resuscitative fluids (FP24 or normal saline). Subsequent samples are drawn at ED arrival and hours 2, 4, 6, 12, 24, 48 and days 5 and 7 after injury. The samples comprise a comprehensive battery of coagulation and other biochemical assays detailed in figure 2, and are typical for each time point with the exception of the field sample which lacks a lactate measurement (due to sample handling constraints) and the addition of a hepatic function panel at the 72 hour time point. At 28 days post-injury, mortality, complications, and other outcomes data are finalized.