Effects of particle rigidity on rolling velocity of particles along an adhesive surface [reproduced with permission from 5]. (A) Illustration of expected rolling mechanism of rigid vWF-targeted particles (top) versus flexible vWF-targeted particles (bottom) along a vWF-coated surface. (B) Rolling velocities of liposomes with a range of membrane flexibilities. *1, EYL/DPPE = 10/1; 2, POPC/DPPE = 10/1; 3, EYL/cholesterol/DPPE = 5/5/1; 4, POPC/cholesterol/DPPE = 5/5/1; 5, DPPC/cholesterol/DPPE = 5/5/1 (by mol).