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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Lupus. 2015 Jan 16;24(9):900–908. doi: 10.1177/0961203314566635

Table 3.

Health-Related Quality of Life Assessment Outcomes

THA TKA

SLE
N = 54
OA
N = 108
P-Value SLE
N = 45
OA
N = 90
P-Value
Pre-operative WOMAC Painb 42.5 ± 19.9 52.7 ± 17.3 0.01* 42.6 ± 17.3 48.4 ± 15.9 0.14
Two-Year WOMACb Pain 91.1 ± 12.4 92.1 ± 14.7 0.77 85.7 ± 14.6 88.6 ± 15.4 0.50
Pre-operative WOMAC Functionb 38.8 ± 21.0 48.0 ± 19.2 0.045* 42.1 ± 17.0 46.8 ± 18.0 0.30
Two-Year WOMAC Functionb 86.4 ± 17.4 90.8 ± 15.4 0.30 83.7 ± 16.3 85.1 ± 17.4 0.77
Pre-operative LEASc 8.0 ± 3.0 9.4 ± 3.0 0.03 8.4 ± 2.3 9.4 ± 3.1 0.14
Two-Year LEASc 10.8 ± 3.6 12.7 ± 3.1 0.02 10.4 ± 2.5 11.0 ± 3.1 0.42
Pre-Operative EQ-5Dd 0.5 ± 0.2 0.6 ± 0.2 0.16 0.6 ± 0.2 0.6 ± 0.2 0.30
Two-Year EQ-5Dd 0.8 ± 0.2 0.9 ± 0.2 0.17 0.8 ± 0.1 0.9 ± 0.2 0.59
Pre-operative SF-36 PCSe 25.0 ± 6.4 31.7 ± 8.6 0.0001* 27.3 ± 6.7 33.4 ± 8.1 0.001*
Two-Year SF-36 PCSe 40.5 ± 12.1 48.7 ± 10.6 0.01* 40.2.0 ± 7.1 47.2 ± 10.7 0.02*
Pre-operative SF-36 MCSe 45.2 ± 9.4 46.2 ± 13.6 0.71 48.1 ± 13.3 48.7 ± 11.6 0.83
Two-Year SF-36 MCSe 51.4 ± 9.9 50.7 ± 11.5 0.80 54.5 ± 10.2 53.3 ± 7.8 0.62
*

Statistically significant

b

Western Ontario and McMaster Universitites Osteoarthritis Index (WOMAC), scale of 1–100 with a difference of 10 considered a clinically meaningful change in arthritis pain, stiffness, and function

c

Lower Extremity Activity Scale (LEAS), comprised of 12 questions assessing different levels of activity

d

Euro-Qol 5D (EQ-5D), assesses the subjective value placed on one’s health with a score of 1 indicating perfect health and 0 indicating death

e

Short Form-36 (SF-36) Physical Component Summary Score (PCS) and Mental Component Summary Score (MCS), composite subscales of the generic validated patient-reported measure of general health and well-being, a difference of 5 points is considered clinically meaningful