Table 1.
Reference range | Healthy subjects | Chronic hepatitis C | P | NAFLD | P | |
Age (yr) | 44.62 ± 11.19 | 60.83 ± 8.55 | < 0.01 | 49.48 ± 14.58 | 0.082 | |
Sex (male:female) | 44:81 | 12:17 | 0.533 | 16:17 | 0.162 | |
AST (IU/L) | 10 - 34 | 97.17 ± 52.62 | 74.68 ± 42.09 | |||
ALT (IU/L) | 7 - 33 | 114.28 ± 61.87 | 108.52 ± 65.07 | |||
Iron (µg/dL) | 60 - 160 | 146.39 ± 48.19 | 108.73 ± 31.06 | |||
TIBC (µg/dL) | 250 - 410 | 377.93 ± 41.10 | 361.57 ± 42.73 | |||
Transferrin saturation (%) | 20 - 50 | 39.01 ± 13.20 | 30.53 ± 9.80 | |||
Ferritin (ng/mL) | Male: 18 - 294 | 225.95 ± 178.24 | 331.20 ± 283.82 | |||
Female: 6 - 283 | ||||||
Increased serum iron store (%) | 10/29 (34.48) | 12/33 (36.36) |
CHC, chronic hepatitis C; NAFLD, nonalcoholic fatty liver disease. P value: comparing data obtained from healthy subjects with chronic hepatitis C or NAFLD. The increased serum iron store was defined by transferrin saturation > 50% and/or ferritin > upper normal limit.