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. 2015 Jun 5;126(3):354–362. doi: 10.1182/blood-2015-02-628149

Figure 7.

Figure 7

MUC1-C inhibitor GO-203 is cytotoxic in CTCL primary cells at 48 and 72 hours. (A-D) MUC1 and TCR Vβ rearranged double-positive malignant population of our interest was FACS sorted from 2 of the patients with L-CTCL (Figure 2D) and treated with varying concentrations (3.5, 5, and 7.5 μM) of GO-203 and CP-2 daily. Cell viability assessed at 48 (A and B) and 72 hours (C and D) demonstrated increased sensitivity to GO-203 in comparison with CP-2 and untreated cells that were statistically significant. Experiment was performed in triplicate. Asterisk indicates a statistically significant P value of <.05.