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Immunohistochemical localization of MMP-1 in gastric epithelial cells. A and B: subject treated with PPIs and with normal serum gastrin. C and D: control subject with normal serum gastrin. E and F: two different subjects with elevated serum gastrin (>200 pM), both on PPIs. Note staining in glandular cells (arrows), but light staining in stroma, mucus neck, and surface epithelial cells. A and C: ×10; other panels: ×20.
