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Exercise training prevented exaggerated hemodynamic responses to chemoreflex activation in CHF. Mean values for peak change in RBF, RVC, AP, and heart rate (HR) from baseline during exposure to hypoxia (FiO2 10%) are shown. The changes in RBF, RVC, AP, and HR were significantly enhanced after pacing in CHF-SED animals; however, this effect was attenuated by EXT and carotid body denervation (CBD) (FiO2 10%, SaO2 80%). *P < 0.05 vs. prepace; #P < 0.05 vs. CHF SED.
